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1.
Nat Food ; 2(5): 326-329, 2021 May.
Article in English | MEDLINE | ID: covidwho-2304990

ABSTRACT

Future foods, such as microalgae, mycoprotein and mealworm, have been suggested as nutritious and sustainable dietary options. Here we consider one of the most profound, yet neglected, benefits of future foods farming systems-their potential to provide essential nutrition in the face of systemic disturbances-and discuss major barriers to realizing this prospect.

2.
Nature Machine Intelligence ; 3(1):2-8, 2021.
Article in English | ProQuest Central | ID: covidwho-1655656

ABSTRACT

We invited authors of selected Comments and Perspectives published in Nature Machine Intelligence in the latter half of 2019 and first half of 2020 to describe how their topic has developed, what their thoughts are about the challenges of 2020, and what they look forward to in 2021.

3.
Nature Machine Intelligence ; 2(7):365-366, 2020.
Article in English | ProQuest Central | ID: covidwho-1655645

ABSTRACT

Artificial intelligence tools can help save lives in a pandemic. However, the need to implement technological solutions rapidly raises challenging ethical issues. We need new approaches for ethics with urgency, to ensure AI can be safely and beneficially used in the COVID-19 response and beyond.

4.
Mar Biotechnol (NY) ; 23(1): 149-155, 2021 Feb.
Article in English | MEDLINE | ID: covidwho-1074429

ABSTRACT

An array of infections, including the novel coronavirus (SARS-CoV-2), trigger macrophage activation syndrome (MAS) and subsequently hypercytokinemia, commonly referred to as a cytokine storm (CS). It is postulated that CS is mainly responsible for critical COVID-19 cases, including acute respiratory distress syndrome (ARDS). Recognizing the therapeutic potential of Spirulina blue-green algae (Arthrospira platensis), in this in vitro stimulation study, LPS-activated macrophages and monocytes were treated with aqueous extracts of Spirulina, cultivated in either natural or controlled light conditions. We report that an extract of photosynthetically controlled Spirulina (LED Spirulina), at a concentration of 0.1 µg/mL, decreases macrophage and monocyte-induced TNF-α secretion levels by over 70% and 40%, respectively. We propose prompt in vivo studies in animal models and human subjects to determine the putative effectiveness of a natural, algae-based treatment for viral CS and ARDS, and explore the potential of a novel anti-TNF-α therapy.


Subject(s)
COVID-19/complications , COVID-19/therapy , Cell Extracts/pharmacology , Cell Extracts/therapeutic use , Cytokine Release Syndrome/etiology , Cytokine Release Syndrome/therapy , Macrophages/drug effects , Monocytes/drug effects , Cells, Cultured , Humans , In Vitro Techniques , Spirulina/chemistry
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